Mad cow disease
Mad cow disease is a worldwide outbreak disease from United Kingdom. It is a cattle brain disease. It is also called Bovine spongiform encephalopathy. The cause of Bovine spongiform encaphalopathy is infection of brain protein called prion. Due to pathogens long time of incubation period infected cattle does not show any symptom initially. After 5 - 6 years later of infection the symptom starts to appear. Meat and bone meal containing pathogens causes infection. It is a zoonotic disease else. Because it can spread animal to another animal. Human also can infect. Cruitzfeldt Jacob disease developed in human when it spread to human from cattle or sheep.